Accuracy of Direct Antimicrobial Susceptibility Testing of Gram-Negative Bacteria from Positive Blood Cultures Using MicroScan System and Value of Using Expert Rules for β-Lactam Agents-Reference-Cited by-同舟云学术

Accuracy of Direct Antimicrobial Susceptibility Testing of Gram-Negative Bacteria from Positive Blood Cultures Using MicroScan System and Value of Using Expert Rules for β-Lactam Agents

Published:2022-03-15 Issue:3 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Jacobs Michael R.¹²^ORCID,Good Caryn E.¹²,Abdelhamed Ayman M.¹²,Bonomo Robert A.³⁴⁵⁶⁷^ORCID

Affiliation:

1. Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA

2. Department of Pathology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA

3. Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA

4. Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, USA

5. Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA

6. Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, USA

7. Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, USA

Abstract

Direct antimicrobial susceptibility testing (AST) of positive blood cultures with Gram-negative bacteria produces results within 24 h, compared to 48 to 96 h with conventional methods. Positive clinical blood cultures were studied, supplemented with contrived blood cultures inoculated with a spectrum of resistant isolates.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.02148-21

Reference22 articles.

1. Emerging Technologies for Microbiologic Diagnosis of Sepsis: The Rapid Determination of Resistance to Antimicrobial Agents Should Be the Key

2. Advancing Diagnostic Stewardship for Healthcare-Associated Infections, Antibiotic Resistance, and Sepsis

3. Understanding and Managing Sepsis in Patients With Cancer in the Era of Antimicrobial Resistance

4. Antimicrobial resistance prevalence, rates of hospitalization with septicemia and rates of mortality with sepsis in adults in different US states

5. Rapid Antimicrobial Susceptibility Testing Methods for Blood Cultures and Their Clinical Impact

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Rapid Antimicrobial Susceptibility Testing Using the MicroScan System: Performance Evaluation of a 4-Hour Bacterial Cultivation From Positive Blood Cultures;Current Microbiology;2024-07-09

2. Evaluation of three protocols for direct susceptibility testing for Gram-negative rods from flagged positive blood culture bottles;Microbiology Spectrum;2024-04-02

3. Rapid Drug Susceptibility Testing to Preserve Antibiotics;Methods in Molecular Biology;2024

4. Recent Advances in Direct Blood Culture Phenotypic Antimicrobial Susceptibility Testing;Clinical Microbiology Newsletter;2022-12