Comparison of In Vitro Activities of Gatifloxacin and Ciprofloxacin against Four Taxa of Rapidly Growing Mycobacteria-Reference-Cited by-同舟云学术

Comparison of In Vitro Activities of Gatifloxacin and Ciprofloxacin against Four Taxa of Rapidly Growing Mycobacteria

Published:2002-10 Issue:10 Volume:46 Page:3283-3285
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Brown-Elliott Barbara A.¹,Wallace Richard J.¹,Crist Christopher J.¹,Mann Linda¹,Wilson Rebecca W.¹

Affiliation:

1. Department of Microbiology, University of Texas Health Center, Tyler, Texas 75708

Abstract

ABSTRACT By using current NCCLS broth microdilution methods, we found that gatifloxacin inhibited 90% of the isolates of the Mycobacterium fortuitum group at ≤0.12 μg/ml and 90% of the Mycobacterium chelonae isolates at ≤4 μg/ml. Gatifloxacin was generally fourfold more active than ciprofloxacin. We recommend that both gatifloxacin and ciprofloxacin be tested routinely against rapidly growing mycobacteria.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.46.10.3283-3285.2002

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