TEM-103/IRT-28 β-Lactamase, a New TEM Variant Produced by Escherichia coli BM4511-Reference-Cited by-同舟云学术

TEM-103/IRT-28 β-Lactamase, a New TEM Variant Produced by Escherichia coli BM4511

Published:2002-11 Issue:11 Volume:46 Page:3627-3629
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Alonso Rodrigo¹,Gerbaud Guy¹,Galimand Marc¹,Courvalin Patrice¹

Affiliation:

1. Unité des Agents Antibactériens, Institut Pasteur, 75724 Paris Cedex 15, France

Abstract

ABSTRACT Clinical isolate Escherichia coli BM4511 was resistant to broad-spectrum penicillins in the presence or in the absence of β-lactamase inhibitors but remained susceptible to cephalosporins. Resistance was due to production of a new TEM-type β-lactamase, designated TEM-103/IRT-28, characterized by the Arg 275 Leu substitution and encoded by the ca. 62-kb pIP845 conjugative plasmid of the IncI1 incompatibility group.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.46.11.3627-3629.2002

Reference19 articles.

1. Ambler, R. P., A. F. Coulson, J. M. Frère, J. M. Ghuysen, B. Joris, M. Forsman, R. C. Levesque, G. Tiraby, and S. G. Waley. 1991. A standard numbering scheme for the class A β-lactamases. Biochem. J.276:269-270.

2. Molecular Characterization of TEM-59 (IRT-17), a Novel Inhibitor-Resistant TEM-Derived β-Lactamase in a Clinical Isolate of Klebsiella oxytoca

3. Bonomo, R. A., S. A. Rudin, and D. M. Shlaes. 1997. Tazobactam is a potent inactivator of selected inhibitor-resistant class A β-lactamases. FEMS Microbiol. Lett.148:59-62.

4. Properties of IRT-14 (TEM-45), a newly characterized mutant of TEM-type beta-lactamases

5. Incompatibility Groups and the Classification of fi − Resistance Factors

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