Molecular Evidence for Nosocomial Transmission of Human Immunodeficiency Virus from a Surgeon to One of His Patients

Author:

Blanchard Alain1,Ferris Stéphane1,Chamaret Sophie1,Guétard Denise1,Montagnier Luc1

Affiliation:

1. Unité d’Oncologie Virale, Institut Pasteur, 75724 Paris Cedex 15, France

Abstract

ABSTRACT We have investigated the molecular evidence in favor of the transmission of human immunodeficiency virus (HIV) from an HIV-infected surgeon to one of his patients. After PCR amplification, the env and gag sequences from the viral genome were cloned and sequenced. Phylogenetic analysis revealed that the viral sequences derived from the surgeon and his patient are closely related, which strongly suggests that nosocomial transmission occurred. In addition, these viral sequences belong to group M of HIV type 1 but are divergent from the reference sequences of the known subtypes.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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