MAL11 and MAL61 encode the inducible high-affinity maltose transporter of Saccharomyces cerevisiae

Author:

Cheng Q1,Michels C A1

Affiliation:

1. Department of Biology, Queens College, CUNY, Flushing 11367.

Abstract

We have investigated the transport of maltose in a genetically defined maltose-fermenting strain of Saccharomyces cerevisiae carrying the MAL1 locus. Two kinetically different systems were identified: a high-affinity transporter with a Km of 4 mM and a low-affinity transporter with a Km of 70 to 80 mM. The high-affinity maltose transporter is maltose inducible and is encoded by the MAL11 (and/or MAL61) gene of the MAL1 (and/or MAL6) locus. The low-affinity maltose transporter is expressed constitutively and is not related to MAL11 and/or MAL61. Both maltose transporters are subject to glucose-induced inactivation.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference22 articles.

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3. MAL63 codes for a positive regulator of maltose fermentation in Saccharomyces cerevisiae;Chang Y. S.;Curr. Genet.,1988

4. Identification and characterization of the maltose permease in a genetically defined Saccharomyces strain;Chang Y. S.;J. Bacteriol.,1989

5. Structural and functional analysis of the MALI locus of Saccharomyces cerevisiae;Charron M. J.;Mol. Cell. Biol.,1986

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