Evidence that Neurons Harbor Latent Herpes Simplex Virus-Reference-Cited by-同舟云学术

Evidence that Neurons Harbor Latent Herpes Simplex Virus

Published:1974-05 Issue:5 Volume:9 Page:946-951
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Cook M. L.¹,Bastone V. B.¹,Stevens J. G.¹

Affiliation:

1. Reed Neurological Research Center and Department of Microbiology and Immunology, UCLA School of Medicine, Los Angeles, California 90024

Abstract

The cell type(s) harboring latent herpes simplex virus in the spinal ganglia of mice was investigated. Taken together, results from immunofluorescence, electron microscopic, autoradiographic, and in situ nucleic acid hybridization methods suggest strongly that, in mice, latent virus is maintained in neurons.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.9.5.946-951.1974

Reference21 articles.

1. Recovery of herpes-simplex virus from human trigeminal ganglions;Baringer J. R.;N. Engl. J. Med.,1973

2. Herpesvirus hominis: isolation from human trigeminal ganglion;Bastian F. O.;Science,1972

3. Replication of varicella-zoster virus in cell culture: an ultrastructural study;Cook M. L.;J. Ultrastruct. Res.,1970

4. Pathogenesis of herpetic neuritis and ganglionitis in mice: evidence for intra-axonal transport of infection;Cook M. L.;Infect. Immunity,1973

5. Fenner F. 1968. The biology of animal viruses vol. 2. Academic Press Inc. New York.

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