Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureus

Author:

Dorado-Morales Pedro1,Garcillán-Barcia M. Pilar2,Lasa Iñigo1ORCID,Solano Cristina1ORCID

Affiliation:

1. Laboratory of Microbial Pathogenesis, Navarrabiomed–Universidad Pública de Navarra–Complejo Hospitalario de Navarra, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Navarra, Spain

2. Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria—Consejo Superior de Investigaciones Científicas, Santander, Cantabria, Spain

Abstract

Plasmids are major agents in the spread of antibiotic resistance genes among bacteria. How plasmids and their hosts coevolve to reduce the fitness cost associated with plasmid carriage when bacteria grow in an antibiotic-free environment is not well understood.

Funder

Ministerio de Ciencia, Innovación y Universidades

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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