Central Role of Sibling Small RNAs NgncR_162 and NgncR_163 in Main Metabolic Pathways of Neisseria gonorrhoeae

Author:

Steiner Thomas1,Zachary Marie2,Bauer Susanne2,Müller Martin J.3,Krischke Markus3,Radziej Sandra1,Klepsch Maximilian2,Huettel Bruno4,Eisenreich Wolfgang1,Rudel Thomas25ORCID,Beier Dagmar2

Affiliation:

1. Bavarian NMR Center–Structural Membrane Biochemistry, Department of Chemistry, Technical University of Munich, Garching, Germany

2. Chair of Microbiology, Theodor-Boveri-Institute, University of Würzburg, Würzburg, Germany

3. Department of Pharmaceutical Biology, Julius von Sachs Institute, University of Würzburg, Würzburg, Germany

4. Max Planck Genome Centre, Cologne, Germany

5. Helmholtz Institute for RNA-Based Infection Research (HIRI), Helmholtz Center for Infection Research (HZI), Würzburg, Germany

Abstract

Neisseria gonorrhoeae is a major human pathogen which infects more than 100 million people every year. An alarming development is the emergence of gonococcal strains that are resistant against virtually all antibiotics used for their treatment.

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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