Role of Small Hydrophobic Protein of J Paramyxovirus in Virulence-Reference-Cited by-同舟云学术

Role of Small Hydrophobic Protein of J Paramyxovirus in Virulence

Published:2018-10-15 Issue:20 Volume:92 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Abraham Mathew¹,Arroyo-Diaz Nicole Michelle¹,Li Zhuo¹,Zengel James¹,Sakamoto Kaori²,He Biao¹

Affiliation:

1. Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA

2. Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA

Abstract

Paramyxoviruses are associated with many devastating diseases in animals and humans. J paramyxovirus (JPV) was isolated from moribund mice in Australia in 1972. Newly isolated viruses, such as Beilong virus (BeiPV) and Tailam virus (TlmPV), have genome structures similar to that of JPV. A new paramyxovirus genus, Jeilongvirus , which contains JPV, BeiPV, and TlmPV, has been proposed. Small hydrophobic (SH) protein is present in many paramyxoviruses. Our present study investigates the role of SH protein of JPV in pathogenesis in its natural host. Understanding the pathogenic mechanism of Jeilongvirus is important to control and prevent potential diseases that may emerge from this group of viruses.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00653-18

Reference29 articles.

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