Induction of Escherichia coli Chromosomal mazEF by Stressful Conditions Causes an Irreversible Loss of Viability-Reference-Cited by-同舟云学术

Induction of Escherichia coli Chromosomal mazEF by Stressful Conditions Causes an Irreversible Loss of Viability

Published:2006-05 Issue:9 Volume:188 Page:3420-3423
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Kolodkin-Gal Ilana¹,Engelberg-Kulka Hanna¹

Affiliation:

1. Department of Molecular Biology, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel

Abstract

ABSTRACT mazEF is a stress-induced toxin-antitoxin module located on the chromosomes of many bacteria. Here we induced Escherichia coli chromosomal mazEF by various stressful conditions. We found an irreversible loss of viability, which is the basic characteristic of cell death. These results further support our previous conclusion that E. coli mazEF mediation of cell death is not a passive process, but an active and genetically “programmed” death response.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.188.9.3420-3423.2006

Reference40 articles.

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