Suppression of JAK-STAT Signaling by Epstein-Barr Virus Tegument Protein BGLF2 through Recruitment of SHP1 Phosphatase and Promotion of STAT2 Degradation-Reference-Cited by-同舟云学术

Suppression of JAK-STAT Signaling by Epstein-Barr Virus Tegument Protein BGLF2 through Recruitment of SHP1 Phosphatase and Promotion of STAT2 Degradation

Published:2021-09-27 Issue:20 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Jangra Sonia¹,Bharti Aradhana¹,Lui Wai-Yin²,Chaudhary Vidyanath²,Botelho Michael George¹,Yuen Kit-San²³,Jin Dong-Yan²^ORCID

Affiliation:

1. Faculty of Dentistry, The University of Hong Kong, Sai Yin Pun, Hong Kong

2. School of Biomedical Sciences, The University of Hong Kong, Pokfulam, Hong Kong

3. School of Medical and Health Sciences, Tung Wah College, Kowloon, Hong Kong

Abstract

Epstein-Barr virus (EBV) is an oncogenic virus associated with the development of lymphoid and epithelial malignancies. EBV has to subvert interferon-mediated host antiviral response to replicate and cause diseases.

Funder

FHB | Health and Medical Research Fund

Research Grants Council, University Grants Committee

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01027-21

Reference72 articles.

1. Epstein–Barr Virus: Diseases Linked to Infection and Transformation

2. Epstein–Barr Virus and Cancer