A Nonstructural Protein Responsible for Viral Spread of a Novel Insect Reovirus Provides a Safe Channel for Biparental Virus Transmission to Progeny
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Published:2019-08
Issue:15
Volume:93
Page:
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ISSN:0022-538X
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Container-title:Journal of Virology
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language:en
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Short-container-title:J Virol
Author:
Chen Qian12, Godfrey Kris3, Liu Jiejie2, Mao Qianzhuo2, Kuo Yen-Wen1, Falk Bryce W.1
Affiliation:
1. Department of Plant Pathology, University of California, Davis, California, USA 2. Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, People’s Republic of China 3. Contained Research Facility, University of California, Davis, California, USA
Abstract
The Asian citrus psyllid,
Diaphorina citri
Kuwayama, is an important pest in the worldwide citrus industry. It is the vector of “
Candidatus
Liberibacter asiaticus,” the bacterial pathogen of Huanglongbing, which is currently considered the most destructive disease of citrus worldwide. DcRV was previously identified based on metagenomics surveys for virus discovery. Here, we found that this novel and persistent insect reovirus took advantage of a virus-encoded nonstructural protein, P10, for efficient vertical transmission from parents to progeny. P10 assembled into a virion-packaging tubular structure and was associated with oocytes of female
D. citri
and sperm of males. Consistent with this, knockdown of P10 for either male or female
D. citri
insects inhibited DcRV transmission to offspring. This tubular strategy for viral spread and biparental transmission might serve as a target for controlling viral vertical transmission and population expansion.
Funder
U.S. Department of Agriculture China Scholarship Council
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Reference47 articles.
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