Affiliation:
1. Division of Microbiology and Molecular Genetics, Loma Linda University, Loma Linda, California, USA
Abstract
Leptospira interrogans
, the cause of the zoonotic infection leptospirosis, is found in soil and water contaminated with animal urine.
L. interrogans
survives in complex environments with the aid of 12 chemoreceptors, none of which has been explicitly studied. In this study, we characterized the first
L. interrogans
chemoreceptor,
Li
Aer2, and reported its unique characteristics.
Li
Aer2 is membrane-bound, has three cytoplasmic PAS-heme domains that each bound hexacoordinate
b
-type heme and O
2
turned
Li
Aer2 signaling off.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
3 articles.
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