Interplay between Candida albicans and the Mammalian Innate Host Defense

Abstract

ABSTRACTCandida albicansis both the most common fungal commensal microorganism in healthy individuals and the major fungal pathogen causing high mortality in at-risk populations, especially immunocompromised patients. In this review, we summarize the interplay between the host innate system andC. albicans, ranging from how the host recognizes, responds, and clearsC. albicansinfection to howC. albicansevades, dampens, and escapes from host innate immunity.