Affiliation:
1. Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235-9072.
Abstract
Gen-Probe's DNA probes were evaluated for use in the identification of clinical isolates of Histoplasma capsulatum var. capsulatum and Cryptococcus neoformans. Ninety-five mould-phase fungi were probed, including 41 isolates of H. capsulatum var. capsulatum. Similarly, 98 yeasts, including 42 C. neoformans isolates, were examined by using the C. neoformans DNA probe. In the study, both probes demonstrated 100% specificity and 100% sensitivity. Their use in the clinical laboratory may significantly reduce the time required for definitive identification of fungi.
Publisher
American Society for Microbiology
Reference21 articles.
1. Control for rheumatoid factor in the latex test for cryptococcosis;Bennett J. E.;Am. J. Clin. Pathol.,1971
2. Primary subcultures of Histoplasma capsulatum. 1. Macro-and micromorphology of the mycelial phase;Berliner M.;Sabouraudia,1968
3. Immunoidentification of Histoplasma capsulatum and Blastomyces dermatitidis with commercial exoantigen reagents;Body B. A.;Arch. Pathol. Lab. Med.,1988
4. Evaluation of the modified API 20C system for identification of clinically important yeasts;Buesching W. J.;J. Clin. Microbiol.,1979
5. Sensitivity and specificity of a latex agglutination test for detection of cryptococcal antigen in meningitis;Coovadia Y. M.;S. Afr. Med. J.,1987
Cited by
40 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Genomic analysis of microbial infections;Molecular Medical Microbiology;2024
2. Histoplasma capsulatum (Histoplasmosis);Principles and Practice of Pediatric Infectious Diseases;2023
3. Histoplasma capsulatum (Histoplasmosis);Principles and Practice of Pediatric Infectious Diseases;2018
4. Commercial Methods for Identification and Susceptibility Testing of Fungi;Manual of Commercial Methods in Clinical Microbiology;2016-04-01
5. Cryptococcosis (Cryptococcus neoformans and Cryptococcus gattii);Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases;2015