Stability of Gentamicin in Serum-Reference-Cited by-同舟云学术

Stability of Gentamicin in Serum

Published:1976-11 Issue:5 Volume:10 Page:866-867
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Jones Sue M.¹²,Blazevic Donna J.¹²,Balfour Henry H.¹²

Affiliation:

1. Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota 55455

2. Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455

Abstract

Patients' sera were divided into three portions when the initial gentamicin level was determined and were stored at −20, 4, and 25°C in plastic or glass tubes. Gentamicin levels were repeated after 1 and 2 days of storage at the respective temperatures. There was no significant difference in gentamicin levels among portions, except those from a patient in renal failure with high serum concentrations of carbenicillin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.10.5.866

Reference4 articles.

1. Daniel W. W. 1974. Biostatistics-a foundation for analysis in the health sciences p. 163-166. John Wiley & Sons New York.

2. Rapid gentamicin bioassay using a multiple-antibiotic-resistant strain of Klebsiella pneumoniae;Lund M. E.;Antimicrob. Agents Chemother.,1974

3. McLaughlin J. E. and D. S. Reeves. 1971. Clinical and laboratory evidence for inactivation of gentamicin by carbenicillin. Lancet i:261-264.

4. Laboratory and clinical conditions for gentamicin inactivation by carbenicillin;Riff L. J.;Arch. Intern. Med.,1972

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