Plasmodium falciparum In Vitro Susceptibility to Antimalarial Drugs in Casamance (Southwestern Senegal) during the First 5 Years of Routine Use of Artesunate-Amodiaquine-Reference-Cited by-同舟云学术

Plasmodium falciparum In Vitro Susceptibility to Antimalarial Drugs in Casamance (Southwestern Senegal) during the First 5 Years of Routine Use of Artesunate-Amodiaquine

Published:2006-04 Issue:4 Volume:50 Page:1531-1534
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Agnamey P.¹,Brasseur P.²,de Pecoulas P. Eldin³,Vaillant Michel⁴,Olliaro P.⁵⁶

Affiliation:

1. Laboratoire de Parasitologie-Mycologie, Hôpital Hôtel Dieu, UFR Hôtel Dieu—Broussais, Université Paris V, Paris, France

2. UR 077, Institut de Recherche pour le Développement, Dakar, Sénégal

3. Faculté de Pharmacie, Université de Caen, Caen, France

4. Centre de Recherche Publique—Santé, Luxembourg

5. UNICEF/UNDP/WB/WHO Special Programme for Research & Training in Tropical Diseases, Geneva, Switzerland

6. Unité 3677, Bases thérapeutiques des inflammations et infections, Université Victor Segalen Bordeaux II, Bordeaux, France

Abstract

ABSTRACT We have monitored the in vitro sensitivities of Plasmodium falciparum isolates predeployment and during the deployment of artesunate plus amodiaquine treatment in Mlomp, Casamance (southwestern Senegal) during 2000 to 2004. Parasites remained susceptible to both drugs. Chloroquine resistance levels were high but stable. Quinine continues to be effective.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.50.4.1531-1534.2006

Reference13 articles.

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