Bactericidal Activities of R207910 and Other Newer Antimicrobial Agents against Mycobacterium leprae in Mice-Reference-Cited by-同舟云学术

Bactericidal Activities of R207910 and Other Newer Antimicrobial Agents against Mycobacterium leprae in Mice

Published:2006-04 Issue:4 Volume:50 Page:1558-1560
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Ji Baohong¹,Chauffour Aurélie¹,Andries Koen²,Jarlier Vincent¹

Affiliation:

1. Bactériologie-Hygiène, Faculté de Médecine Pierre et Marie Curie, Université Paris 6, Paris, France

2. Johnson & Johnson Pharmaceutical Research and Development, Beerse, Belgium

Abstract

ABSTRACT As measured by a proportional bactericidal technique in the mouse footpad system, the bactericidal activity against Mycobacterium leprae of R207910 was equal to that of rifapentine, rifampin, or moxifloxacin and significantly greater than those of minocycline, PA-824, and linezolid. These data suggest that R207910 may play an important role in treatment of leprosy.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.50.4.1558-1560.2006

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