Non-Continuous Translation of Coat Protein and Ribonucleic Acid Polymerase Cistrons in MS2 Bacteriophage Ribonucleic Acid-Reference-Cited by-同舟云学术

Non-Continuous Translation of Coat Protein and Ribonucleic Acid Polymerase Cistrons in MS2 Bacteriophage Ribonucleic Acid

Published:1974-01 Issue:1 Volume:117 Page:227-231
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Grubman Marvin J.¹,Nakada Dai¹

Affiliation:

1. Department of Biochemistry, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania 15261

Abstract

In an MS2 phage ribonucleic acid (RNA)-directed in vitro protein-synthesizing system, the coat protein cistron and the adjacent RNA polymerase cistron are translated non-continuously. The ribosomes which have completed the synthesis of coat protein dissociate from the MS2 RNA and do not read through the intercistronic gap. Translation of the adjacent RNA polymerase cistron requires ribosomes other than those translating the coat protein cistron.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.117.1.227-231.1974

Reference21 articles.

1. N-formylmethionyl sRNA as the initiator of protein synthesis;Adams J.;Proc. Nat. Acad. Sci. U.S.A.,1966

2. Release factors mediating termination of complete proteins;Capecchi M. R.;Nature (London),1970

3. Ribosomal subunits and MS2 phage RNA-directed protein synthesis;Grubman M. J.;Nature (London),1969

4. Translation of an RNA viral message in vitro: one-step polypeptide chain elongation;Hsu W. T.;Biochem. Biophys. Res. Commun.,1971

5. Gene order in the bacteriophage R17 RNA: 5'-A protein-coat protein-synthetase-3;Jeppesen P. G. N.;Nature (London),1970

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1. Ribosome recycling by ribosome recycling factor (RRF) ? An important but overlooked step of protein biosynthesis;Advances in Biophysics;1996

2. Reinitiation of translation from the triplet next to the amber termination codon in the absence of ribosome-releasing factor.;Proceedings of the National Academy of Sciences;1981-10-01

3. Early to late switch in bacteriophage T7 development: No translational discrimination between T7 early messenger RNA and late messenger RNA;Journal of Molecular Biology;1976-01

4. The in vitro translation of a terminating signal by a single Escherichia coli ribosome. The fate of the subunits.;Journal of Biological Chemistry;1975-10

5. Isolation of an inhibitor protein of E. coli RNA polymerase from T7 phage infected cell;Nature;1974-11