Pooling Pharyngeal, Anorectal, and Urogenital Samples for Screening Asymptomatic Men Who Have Sex with Men for Chlamydia trachomatis and Neisseria gonorrhoeae

Author:

Durukan Duygu12ORCID,Read Tim R. H.12,Bradshaw Catriona S.12,Fairley Christopher K.12,Williamson Deborah A.3ORCID,De Petra Vesna3,Maddaford Kate2,Wigan Rebecca2,Chen Marcus Y.2,Tran Anne2,Chow Eric P. F.124ORCID

Affiliation:

1. Central Clinical School, Monash University, Melbourne, Victoria, Australia

2. Melbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia

3. Microbiological Diagnostic Unit Public Health Laboratory, Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia

4. Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia

Abstract

Screening for Chlamydia trachomatis and Neisseria gonorrhoeae at the pharyngeal, urogenital, and anorectal sites is recommended for men who have sex with men (MSM). Combining the three individual-site samples into a single pooled sample could result in significant cost savings, provided there is no significant sensitivity reduction. The aim of this study was to examine the sensitivity of pooled samples for detecting chlamydia and gonorrhea in asymptomatic MSM using a nucleic acid amplification test.

Funder

Department of Health | National Health and Medical Research Council

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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