Next-Generation Human Cerebral Organoids as Powerful Tools To Advance NeuroHIV Research-Reference-Cited by-同舟云学术

Next-Generation Human Cerebral Organoids as Powerful Tools To Advance NeuroHIV Research

Published:2021-08-31 Issue:4 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Premeaux Thomas A.¹^ORCID,Mediouni Sonia²,Leda Ana²,Furler Robert L.¹,Valente Susana T.²^ORCID,Fine Howard A.³,Nixon Douglas F.¹^ORCID,Ndhlovu Lishomwa C.¹

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York, USA

2. Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida, USA

3. Meyer Cancer Center, Division of Neuro-Oncology, Department of Neurology, New York-Presbyterian Hospital/Weill Cornell Medicine, New York, New York, USA

Abstract

Long-term effective use of antiretroviral therapy (ART) among people with HIV (PWH) has significantly reduced the burden of disease, yet a cure for HIV has not been universally achieved, likely due to the persistence of an HIV reservoir. The central nervous system (CNS) is an understudied HIV sanctuary.

Funder

HHS | NIH | National Institute on Drug Abuse

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00680-21

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