A Common Pathway for Activation of Host-Targeting and Bacteria-Targeting Toxins in Human Intestinal Bacteria-Reference-Cited by-同舟云学术

A Common Pathway for Activation of Host-Targeting and Bacteria-Targeting Toxins in Human Intestinal Bacteria

Published:2021-08-31 Issue:4 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Bao Yiqiao¹²,Verdegaal Andrew A.¹²,Anderson Brent W.¹²,Barry Natasha A.¹²,He Jing³,Gao Xiang³,Goodman Andrew L.¹²^ORCID

Affiliation:

1. Department of Microbial Pathogenesis, Yale University, New Haven, Connecticut, USA

2. Microbial Sciences Institute, Yale University, New Haven, Connecticut, USA

3. State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong, China

Abstract

The human intestine harbors a highly complex microbial community; interpersonal variation in this community can impact pathogen susceptibility, metabolism, and other aspects of health. Here, we identified and characterized a commensal-targeting antibacterial protein encoded in the gut microbiome.

Funder

HHS | National Institutes of Health

Howard Hughes Medical Institute

Burroughs Wellcome Fund

Taishan Young Scholar Program

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.00656-21

Reference43 articles.