Impact of Polymicrobial Infection on Fitness of Streptococcus gordonii In Vivo

Author:

Pandey Satya D.1,Perpich John D.12,Stocke Kendall S.1,Mansfield Jillian M.3,Kikuchi Yuichiro1,Yakoumatos Lan1,Muszyński Artur4,Azadi Parastoo4,Tettelin Hervé5,Whiteley Marvin6ORCID,Uriarte Silvia M.1,Bagaitkar Juhi78,Vickerman Margaret3,Lamont Richard J.1ORCID

Affiliation:

1. Department of Oral Immunology and Infectious Diseases, University of Louisville, Louisville, Kentucky, USA

2. Department of Pharmaceutical Science, Sullivan University, Louisville, Kentucky, USA

3. Department of Oral Biology, School of Dental Medicine, University at Buffalo, Buffalo, New York, USA

4. Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA

5. Department of Microbiology and Immunology, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA

6. School of Biological Sciences, Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA

7. Center for Microbial Pathogenesis, Nationwide Children's Hospital, Columbus, Ohio, USA

8. Department of Pediatrics, The Ohio State College of Medicine, Columbus, Ohio, USA

Abstract

Bacteria responsible for diseases originating at oral mucosal membranes assemble into polymicrobial communities. However, we know little regarding the fitness determinants of the organisms that initiate community formation.

Funder

HHS | NIH | National Institute of Dental and Craniofacial Research

HHS | NIH | National Institute of General Medical Sciences

US Department of Energy Office of Science, Basic Energy Sciences

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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