Major Role for Cellular MicroRNAs, Long Noncoding RNAs (lncRNAs), and the Epstein-Barr Virus-Encoded BART lncRNA during Tumor Growth <i>In Vivo</i>-Reference-Cited by-同舟云学术

Major Role for Cellular MicroRNAs, Long Noncoding RNAs (lncRNAs), and the Epstein-Barr Virus-Encoded BART lncRNA during Tumor Growth In Vivo

Published:2022-06-28 Issue:3 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Edwards Rachel Hood¹,Raab-Traub Nancy¹²

Affiliation:

1. Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

2. Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

Abstract

This study identified the total effects of EBV and a viral long noncoding RNA (BART lncRNA) on cellular RNA expression when grown as cells in culture and when grown as tumors in immunodeficient mice. The effects on cellular mRNA expression, lncRNA expression, and cellular and viral miR expression were determined using next-generation sequencing (NGS) and bioinformatics functional analysis.

Funder

HHS | NIH | National Cancer Institute

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00655-22

Reference77 articles.

1. EBV-induced oncogenesis

2. Nasopharyngeal Carcinoma: An Evolving Role for the Epstein–Barr Virus

3. Establishment and characterization of three transplantable EBV-containing nasopharyngeal carcinomas

4. Kieff E, Rickinson AB. 2001. Epstein Barr virus and its replication, p 2511–2573. In Knipe DM, Howley PM (ed), Fields virology, 4th ed. Lippincott Williams, and Wilkins, Philadelphia, PA.

5. Novel transcription from the Epstein-Barr virus terminal EcoRI fragment, DIJhet, in a nasopharyngeal carcinoma

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Role of lncRNAs in Helicobacter pylori and Epstein-Barr virus associated gastric cancers;Life Sciences;2024-01

2. Texture analysis of pharynx in chronic phase Epstein-Barr virus infection;Annals of Clinical and Analytical Medicine;2023-05-01

3. Molecular Signaling Pathways in Nasopharyngeal Carcinoma;Medical Radiology;2023