Rift Valley Fever Virus Nucleoprotein Triggers Autophagy to Dampen Antiviral Innate Immune Responses-Reference-Cited by-同舟云学术

Rift Valley Fever Virus Nucleoprotein Triggers Autophagy to Dampen Antiviral Innate Immune Responses

Published:2023-04-27 Issue:4 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Zhu Xiangtao¹²,Guan Zihan¹²,Fang Yujie¹²,Zhang Yulan¹,Guan Zhenqiong¹²,Li Shufen¹²,Peng Ke¹²³^ORCID

Affiliation:

1. State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Antiviral Research, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, People’s Republic of China

2. University of Chinese Academy of Sciences, Beijing, China

3. Hubei Jiangxia Laboratory, Wuhan, Hubei, China

Abstract

We showed that RVFV infection induced the complete autophagy process. Depletion of the core autophagy genes ATG5 , ATG7 , or SQSTM1 or pharmacologic inhibition of autophagy in macrophages strongly suppressed RVFV replication.

Funder

MOST | National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01814-22

Reference52 articles.

1. Molecular aspects of Rift Valley fever virus and the emergence of reassortants

2. Rift Valley fever: biology and epidemiology