Determination of antimicrobial susceptibilities of Canadian isolates of Haemophilus influenzae and characterization of their beta-lactamases. Canadian Haemophilus Study Group

Author:

Scriver S R1,Walmsley S L1,Kau C L1,Hoban D J1,Brunton J1,McGeer A1,Moore T C1,Witwicki E1

Affiliation:

1. Department of Microbiology, Mount Sinai Hospital, University of Toronto, Ontario, Canada.

Abstract

Susceptibility testing of 1,688 Haemophilus influenzae isolates found 484 ampicillin-resistant strains; 474 strains (28.4%) were beta-lactamase positive, and 5 strains (0.4%) were non-beta-lactamase producers. Restriction enzyme digestion of the beta-lactamase amplicon determined that, of 157 strains, 11 (7.0%) contained ROB-1 beta-lactamase and 146 (93.0%) contained a TEM-type beta-lactamase.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference16 articles.

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3. Update on mechanisms and prevalence of antimicrobial resistance in Haemophilus influenzae;Jorgensen J. H.;Clin. Infect. Dis.,1992

4. Sequence analysis and evolutionary perspectives of ROB-1 P-lactamase;Juteau J.;Antimicrob. Agents Chemother.,1990

5. Kilan M. 1991. Haemophilus p. 463-470. In A. Balows W. J. Hausler Jr. K. L. Herrmann H. D. Isenberg and H. J. Shadomy (ed.) Manual of clinical microbiology 5th ed. American Society for Microbiology Washington D.C.

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