Nontoxic lipopolysaccharide from Rhodopseudomonas sphaeroides ATCC 17023

Author:

Strittmatter W,Weckesser J,Salimath P V,Galanos C

Abstract

Chemical analysis of the lipopolysaccharide from Rhodopseudomonas sphaeroides ATCC 17023, isolated by the phenol-chloroform-petroleum ether method, revealed the presence of glucuronic acid, 2-keto-3-deoxyoctonate, threonine, and phosphorus in the polysaccharide moiety. The lipid A component contained glucosamine, glucosamine phosphate, amide-bound 3-oxotetradecanoic acid and 3-hydroxytetradecanoic acid, and ester-bound 3-hydroxydecanoic acid and 7-tetradecenoic acid. Structural similarity of the lipid A from R. sphaeroides ATCC 17023 to enterobacterial lipid A is indicated by the existence of a serological cross-reaction occurring between the lipid A from R. sphaeroides ATCC 17023 and that from Salmonella minnesota R595. The lipopolysaccharide and lipid A of R. sphaeroides, however, were found to be neither toxic in mice nor pyrogenic in rabbits.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference30 articles.

1. AUtorenkollektlv. 1976. Katalytische Hydrierung von Carbonylverbindungen p. 539-543. In Organikum vol. 15. VEB Deutscher Verlag der Wissenschaften Berlin.

2. A new specific color reaction of hexuronic acids;Dische Z.;J. Biol. Chem.,1947

3. Galanos C. M. Freudenberg S. Hase F. Jay and E. Ruschmann. 1977. Biological activities and immunological properties of lipid A p. 269-276. In D. Schlessinger (ed.) Microbiology-1977. American Society for Microbiology. Washington D.C.

4. Galactosamine-induced sensitization of the lethal effects of endotoxin;Galanos C.;Proc. Natl. Acad. Sci. U.S.A.,1979

5. A new method for extraction of R lipopolysaccharides;Galanos C.;Eur. J. Biochem.,1969

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