Human CD4+ T-cell recognition of influenza A virus hemagglutinin after subunit vaccination-Reference-Cited by-同舟云学术

Human CD4+ T-cell recognition of influenza A virus hemagglutinin after subunit vaccination

Published:1996-07 Issue:7 Volume:70 Page:4787-4790
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Gelder C M¹,Lamb J R¹,Askonas B A¹

Affiliation:

1. Infection and Immunity Section, Department of Biology, Imperial College of Science, Technology and Medicine, London, United Kingdom.

Abstract

We have examined human CD4+ T-cell recognition of influenza A/Beijing/32/92 (H3N2) virus hemagglutinin following influenza virus HANA subunit vaccination. CD4+ T-cell repertoires were dominated by recognition of epitopes located in conserved regions of the molecule, in a major histocompatibility complex class II haplotype-dependent manner, analogous to that observed following natural infection.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.70.7.4787-4790.1996

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