The Xenogeneic Silencer Histone-Like Nucleoid-Structuring Protein Mediates the Temperature and Salinity-Dependent Regulation of the Type III Secretion System 2 in Vibrio parahaemolyticus-Reference-Cited by-同舟云学术

The Xenogeneic Silencer Histone-Like Nucleoid-Structuring Protein Mediates the Temperature and Salinity-Dependent Regulation of the Type III Secretion System 2 in Vibrio parahaemolyticus

Published:2023-01-26 Issue:1 Volume:205 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Pratama Andre¹^ORCID,Ishii Eiji¹,Kodama Toshio²,Iida Tetsuya¹³⁴⁵^ORCID,Matsuda Shigeaki¹³^ORCID

Affiliation:

1. Department of Bacterial Infections, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan

2. Department of Bacteriology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan

3. Section of Bacterial Drug Resistance Research, Japan-Thailand Research Collaboration Center on Emerging and Re-emerging Infections, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan

4. Department of Infection Metagenomics, Genome Information Research Center, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan

5. Center for Infectious Disease Education and Research (CiDER), Osaka University, Osaka, Japan

Abstract

In the major seafood-borne pathogen Vibrio parahaemolyticus , the type III secretion system 2 (T3SS2) is a major virulence factor that is responsible for the enterotoxicity of this bacterium. The expression of T3SS2 varies according to changes in temperature and salinity, but the mechanism via which T3SS2 expression is regulated in response to such physical cues remains unknown.

Funder

MEXT | Japan Society for the Promotion of Science

Institute for Fermentation, Osaka

Takeda Science Foundation

Nagasaki University

BIKEN Foundation

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00266-22

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