High Prevalence of PER-1 Extended-Spectrum β-Lactamase-Producing Acinetobacter spp. in Korea

Author:

Yong Dongeun12,Shin Jong Hee3,Kim Sinyoung12,Lim Youngsik4,Yum Jong Hwa24,Lee Kyungwon124,Chong Yunsop12,Bauernfeind Adolf5

Affiliation:

1. Department of Laboratory Medicine

2. Research Institute of Bacterial Resistance

3. Department of Laboratory Medicine, Chonnam University Medical School, Kwangju, Korea

4. BK21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul

5. MICOER Institute, Munich, Germany

Abstract

ABSTRACT PER-1, an extended-spectrum β-lactamase, has been reported only in Europe. We detected PER-1 in 53 of 97 acinetobacters in Korea, mainly in the sputum of intensive care unit patients. Pulsed-field gel electrophoresis analysis suggested that clonal spread had occurred. Only PCR reliably detected PER-1 producers. PER-1 producers may also exist in other Asian countries.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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