Arachidonic acid metabolism in polymorphonuclear leukocytes from patients with chronic granulomatous disease-Reference-Cited by-同舟云学术

Arachidonic acid metabolism in polymorphonuclear leukocytes from patients with chronic granulomatous disease

Published:1983-06 Issue:3 Volume:40 Page:1230-1233
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Smith D M,Walsh C E,Dechatelet L R,Waite M

Abstract

The effect of the calcium ionophore A23187 on the release and metabolism of [3H]arachidonic acid was examined in normal polymorphonuclear leukocytes and those obtained from patients with chronic granulomatous disease. The ionophore A23187 which stimulates oxidative metabolism in normal polymorphonuclear leukocytes was ineffective in increasing oxidative metabolism (chemiluminescence) in polymorphonuclear leukocytes from patients with chronic granulomatous disease. However, the ionophore A23187 stimulated the release of [3H]arachidonic acid from chronic granulomatous disease neutrophil phospholipids and stimulated its metabolism into hydroxyeicosatetraenoic acids and leukotrienes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.40.3.1230-1233.1983

Reference36 articles.

1. Chemiluminescence from eukaryotic and prokaryotic cells: reducing potential and oxygen requirements;Alien R. C.;Photochem. Photobiol.,1979

2. Correlation of metabolic and chemiluminescent responses of granulocytes from three female siblings with chronic granulomatous disease;Alien R. C.;J. Infect. Dis.,1977

3. Oxygen-dependent microbial killing by phagocytes;Bablor B. M.;N. Engl. J. Med.,1978

4. Active oxygen species and the functions of phagocytic leukocytes. Annu;Badwey J. A.;Rev. Biochem.,1980

5. Diglyceride lipase: a pathway for arachidonate release from human platelets;Beli R. I.;Proc. Natl. Acad. Sci. U.S.A.,1979

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1. The Role of Phagocytes in Non-Infectious Diseases;Phagocytes and Disease;1989

2. Chronic Granulomatous Disease;Advances in Human Genetics;1987

3. Differences in the effect of arachidonic acid on polymorphonuclear and mononuclear leukocyte function;Biochimica et Biophysica Acta (BBA) - General Subjects;1984-09-28