Establishment and Validation of Pathogenic CS17 + and CS19 + Enterotoxigenic Escherichia coli Challenge Models in the New World Primate Aotus nancymaae

Abstract

Enterotoxigenic Escherichia coli (ETEC) is a common cause of diarrheal illness in the military, travelers, and children living in low- to-middle income countries. Increased antibiotic resistance, the absence of a licensed vaccine, and the lack of broadly practical therapeutics perpetuate the significant health and financial burden resulting from ETEC infection.