Lot Quality Assurance Sampling of Sputum Acid-Fast Bacillus Smears for Assessing Sputum Smear Microscopy Centers

Author:

Selvakumar N.1,Murthy B. N.2,Prabhakaran E.1,Sivagamasundari S.1,Vasanthan Samuel1,Perumal M.3,Govindaraju R.4,Chauhan L. S.5,Wares Fraser6,Santha T.1,Narayanan P. R.1

Affiliation:

1. Tuberculosis Research Centre

2. National Institute of Epidemiology, Indian Council of Medical Research, Chennai

3. State TB Office, Tamil Nadu

4. District Tuberculosis Centre, Tiruvallur

5. Central TB Division, Ministry of Health and Family Welfare

6. Stop TB Unit, World Health Organization, SEARO, New Delhi, India

Abstract

ABSTRACT Assessment of 12 microscopy centers in a tuberculosis unit by blinded checking of eight sputum smears selected by using a lot quality assurance sampling (LQAS) method and by unblinded checking of all positive and five negative slides, among the slides examined in a month in a microscopy centre, revealed that the LQAS method can be implemented in the field to monitor the performance of acid-fast bacillus microscopy centers in national tuberculosis control programs.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference10 articles.

1. Central Tuberculosis Division Revised National Tuberculosis Control Programme. 2001. Manual for laboratory technicians. Directorate General of Health Services Ministry of Health and Family Welfare Government of India New Delhi India.

2. Central Tuberculosis Division Revised National Tuberculosis Control Programme. 2001. Module for senior tuberculosis laboratory supervisor. Directorate General of Health Services Ministry of Health and Family Welfare Government of India New Delhi India.

3. Central Tuberculosis Division Revised National Tuberculosis Control Programme. 2001. Quality assurance network in sputum smear microscopy under RNTCP. [Online.] http://www.tbcindia.org/QUALITYASSURANCE.pdf .

4. Gupte, M. D., and B. Narasimhamurthy. 1999. Lot quality assurance sampling (LQAS) for monitoring a leprosy elimination program. Int. J. Lepr. Other Mycobact. Dis.67:143-149.

5. Khatri, G. R., and T. R. Frieden. 2000. The status and prospects of tuberculosis control in India. Int. J. Tuberc. Lung Dis.4:193-200.

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