Effect of Rifampin on Cutaneous Hypersensitivity to Purified Protein Derivative in Humans-Reference-Cited by-同舟云学术

Effect of Rifampin on Cutaneous Hypersensitivity to Purified Protein Derivative in Humans

Published:1973-12 Issue:6 Volume:4 Page:607-611
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Mukerjee P.¹,Schuldt S.¹,Kasik J. E.¹

Affiliation:

1. Department of Internal Medicine, University of Iowa, College of Medicine, and V.A. Hospital, Iowa City, Iowa 52240

Abstract

The effect of rifampin on cutaneous hypersensitivity was studied in 11 tuberculous patients. A suppressive effect was noted in eight patients, five of whom developed a negative response to the strength of purified protein derivative to which they had been shown to be previously sensitive. In one instance complete anergy to purified protein derivative was noted. It appears that rifampin has immunosuppressive effects in some patients when used in conventional doses.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.4.6.607

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