Changes to the Simian Immunodeficiency Virus (SIV) Reservoir and Enhanced SIV-Specific Responses in a Rhesus Macaque Model of Functional Cure after Serial Rounds of Romidepsin Administrations

Author:

Kleinman Adam J.1,Sivanandham Sindhuja12,Sette Paola2,Sivanandham Ranjit12,Policicchio Benjamin B.3,Xu Cuiling2,Penn Ellen1,Brocca-Cofano Egidio2,Le Hingrat Quentin12,Ma Dongzhu12,Pandrea Ivona23,Apetrei Cristian13ORCID

Affiliation:

1. Division of Infectious Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

2. Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

3. Department of Infectious Diseases and Immunology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

Abstract

HIV cure is sought after due to the prevalence of comorbidities that occur in persons with HIV. One of the most investigated HIV cure strategies is the “shock and kill” approach.

Funder

HHS | NIH | National Heart, Lung, and Blood Institute

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Antiviral Targets and Known Antivirals (HAART);Infectious Diseases;2023-12-20

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