Evaluation of the New GenoType Mycobacterium Assay for Identification of Mycobacterial Species-Reference-Cited by-同舟云学术

Evaluation of the New GenoType Mycobacterium Assay for Identification of Mycobacterial Species

Published:2006-02 Issue:2 Volume:44 Page:334-339
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Russo Cristina¹,Tortoli Enrico²,Menichella Donato¹

Affiliation:

1. Microbiology Laboratory, Bambino Gesù Hospital, Rome

2. Regional Reference Center for Mycobacteria, Microbiology and Virology Laboratory, Careggi Hospital, Florence, Italy

Abstract

ABSTRACT The new commercial assay GenoType Mycobacterium, intended for the identification of mycobacteria, was evaluated with a panel of 197 strains belonging to 86 different taxa. The system, which relies on solid-phase reverse hybridization, is composed of two different kits: GenoType CM for the identification of more frequently detected mycobacterial species and GenoType AS for less common species. The sensitivity and specificity were 97.9% and 92.4% for the CM kit and 99.3% and 99.4% for the AS kit. Our results show that the system may represent a useful tool to substantially enlarge the number of mycobacteria that can be reliably identified in clinical laboratories.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.44.2.334-339.2006

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