trans -Sialidase Inhibition Assay, a Highly Sensitive and Specific Diagnostic Test for Chagas' Disease-Reference-Cited by-同舟云学术

trans -Sialidase Inhibition Assay, a Highly Sensitive and Specific Diagnostic Test for Chagas' Disease

Published:2001-01 Issue:1 Volume:8 Page:187-189
ISSN:1071-412X
Container-title:Clinical Diagnostic Laboratory Immunology
language:en
Short-container-title:Clin Diagn Lab Immunol

Author:

Buchovsky A. S.¹,Campetella O.²,Russomando G.³,Franco L.³,Oddone R.³,Candia N.³,Luquetti A.⁴,Gonzalez Cappa S. M.¹,Leguizamon M. S.¹

Affiliation:

1. Departamento de Microbiologı́a, Facultad de Medicina, Universidad de Buenos Aires,1 and

2. Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martin,2 Buenos Aires, Argentina;

3. Instituto de Ciencias de la Salud, Universidad Nacional de Asunción, Paraguay3; and

4. Instituto de Patologia Tropical e Saude Publica, Universidad Federal de Goias, Goiania, Brazil4

Abstract

ABSTRACT For the diagnosis of Chagas' disease, the trans -sialidase inhibition assay was able to resolve the results for samples with borderline results, to detect as positive 60% of samples that were negative by conventional serology, and to discriminate idiopathic from chagasic megaviscera or cardiopathy. No cross-reaction with sera from patients with other diseases was observed.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CDLI.8.1.187-189.2001

Reference12 articles.

1. Detection of Trypanosoma cruzi in blood specimens of chronic chagasic patients by polymerase chain reaction amplification of kinetoplast minicircle DNA: comparison with serology and xenodiagnosis

2. Medium scale production and purification to homogeneity of a recombinant trans-sialidase from Trypanosoma cruzi.;Buschiazzo A.;Cell. Mol. Biol.,1996

3. A recombinant Trypanosoma cruzi trans-sialidase lacking the amino acid repeats retains the enzymatic activity.;Campetella O.;Mol. Biochem. Parasitol.,1994

4. Comparison of genes encoding Trypanosoma cruzi antigens.;Frasch A. C. C.;Parasitol. Today,1991

5. Mice infected with Trypanosoma cruzi produce antibodies against the enzymatic domain of trans-sialidase that inhibit its activity

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Evaluación del UMELISA CHAGAS® con la incorporación de nuevos péptidos monoméricos y quiméricos representativos de diferentes regiones de Trypanosoma cruzi;Biomédica;2021-05-31

2. Parasite-host glycan interactions during Trypanosoma cruzi infection: trans-Sialidase rides the show;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2020-05

3. Diagnostic Applicability of Neutralizing Antibodies to Trypanosoma cruzi Trans-sialidase;Methods in Molecular Biology;2019

4. Chagas disease: an overview of diagnosis;Journal of Microbiology & Experimentation;2018-06-07

5. Chagas Disease Diagnostic Applications;Advances in Parasitology;2017