Author:
Trucksis M,Golub E I,Zabel D J,Depew R E
Abstract
Mutations of the Escherichia coli or Salmonella typhimurium supX genes eliminated deoxyribonucleic acid topoisomerase I. Suppression of a supX amber mutation partially restored the topoisomerase. Multicopy plasmids carrying supX+ caused overproduction of topoisomerase. Thus, these supX genes were identified as topA genes which specify deoxyribonucleic acid topoisomerase I.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
57 articles.
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