Mucosal Immune Profiles Associated with Diarrheal Disease Severity in<i>Shigella</i>- and Enteropathogenic Escherichia coli-Infected Children Enrolled in the Global Enteric Multicenter Study-Reference-Cited by-同舟云学术

Mucosal Immune Profiles Associated with Diarrheal Disease Severity inShigella- and Enteropathogenic Escherichia coli-Infected Children Enrolled in the Global Enteric Multicenter Study

Published:2022-08-30 Issue:4 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Buskirk Amanda D.¹²,Ndungo Esther¹²^ORCID,Shimanovich Avital A.³,Lam Diana¹,Blackwelder William C.¹,Ikumapayi Usman N.⁴,Ma Bing³⁵,Powell Helen⁶,Antonio Martin⁴⁷⁸,Nataro James P.⁹,Kaper James B.³,Pasetti Marcela F.¹²^ORCID

Affiliation:

1. Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA

2. Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, USA

3. Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA

4. Vaccines and Immunity Theme, Medical Research Council Unit The Gambia, Banjul, The Gambia

5. Institute of Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA

6. Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA

7. Microbiology and Infection Unit, The University of Warwick, Coventry, United Kingdom

8. Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

9. University of Virginia School of Medicine, Department of Pediatrics, Charlottesville, Virginia, USA

Abstract

Shigellaand enteropathogenicEscherichia coliare primary agents of moderate to severe diarrhea in children <5 years of age living in resource-poor countries. Repeated bouts of illness lead to lifelong health impairment and even death.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.00538-22

Reference54 articles.

1. Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

2. ENTEROPATHOGENIC ESCHERICHIA COLI OF CLASSIC SEROTYPES ASSOCIATED WITH INFANT DIARRHEA: EPIDEMIOLOGY AND PATHOGENESIS