Diverse Mechanisms of Helicase Loading during DNA Replication Initiation in Bacteria-Reference-Cited by-同舟云学术

Diverse Mechanisms of Helicase Loading during DNA Replication Initiation in Bacteria

Published:2023-04-25 Issue:4 Volume:205 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Blaine Helen C.¹²,Simmons Lyle A.³^ORCID,Stallings Christina L.¹²^ORCID

Affiliation:

1. Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, USA

2. Center for Women’s Infectious Disease Research, Washington University School of Medicine, Saint Louis, Missouri, USA

3. Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA

Abstract

Initiation of DNA replication is required for cell viability and passage of genetic information to the next generation. Studies in Escherichia coli and Bacillus subtilis have established A TPases a ssociated with diverse cellular a ctivities (AAA+) as essential proteins required for loading of the replicative helicase at replication origins.

Funder

Burroughs Wellcome Fund

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00487-22

Reference152 articles.

1. Kornberg A, Baker TA. 1992. DNA Replication. W.H. Freeman & Co., New York, NY.

2. Purified dnaA protein in initiation of replication at the Escherichia coli chromosomal origin of replication.