Detection of Mixed Populations of Clarithromycin-Susceptible and -Resistant Mycobacterium abscessus Strains-Reference-Cited by-同舟云学术

Detection of Mixed Populations of Clarithromycin-Susceptible and -Resistant Mycobacterium abscessus Strains

Published:2022-04-20 Issue:4 Volume:60 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Shallom Shamira J.¹,Zelazny Adrian M.¹^ORCID

Affiliation:

1. Microbiology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA

Abstract

Clarithromycin resistance in Mycobacterium abscessus subsp. abscessus , massiliense , and bolletii occurs through induction of erm (41) or mutations in rrl (23S rRNA) genes. Phenotypic detection of clarithromycin resistance is hindered by the need for extended incubation as well as co-occurrence of mixed populations of M. abscessus

Funder

HHS | NIH | NIH Clinical Center

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/jcm.01694-21

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