A Morbillivirus Infection Shifts DC Maturation Toward a Tolerogenic Phenotype to Suppress T Cell Activation

Author:

Rodríguez-Martín Daniel1,García-García Isabel2,Martín Verónica1,Rojas José Manuel1ORCID,Sevilla Noemí1

Affiliation:

1. Centro de Investigación en Sanidad Animal (CISA-INIA-CSIC), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, Consejo Superior de Investigaciones Científicas, Valdeolmos, Madrid, Spain

2. Departamento de Genética, Fisiología y Microbiología, UD de Genética, Facultad de CC. Biológicas, Universidad Complutense de Madrid, Madrid, Spain

Abstract

Morbilliviruses pose a threat to global health given their high infectivity. The morbillivirus peste des petits ruminants virus (PPRV) severely affects small-ruminant-productivity and leads to important economic losses in communities that rely on these animals for subsistence.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference84 articles.

1. La peste des petite ruminants;Gargadenec L;Bull Serv Zoot Epizoot AOF,1942

2. Global distribution of peste des petits ruminants virus and prospects for improved diagnosis and control

3. Peste Des Petits Ruminants Virus Infection of Small Ruminants: A Comprehensive Review

4. FAO/World Organisation for Animal Health. 2015. Global strategy for the control and eradication of PPR. http://wwwfao.org/3/i4460e.pdf.

5. Morbillivirus Pathogenesis and Virus–Host Interactions

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