Abortive Potency of Chlamydophila abortus in Pregnant Mice Is Not Directly Correlated with Placental and Fetal Colonization Levels

Author:

Bouakane Amel1,Benchaîeb Ilhem1,Rodolakis Annie1

Affiliation:

1. Unité de Recherche Pathologie Infectieuse et Immunologie, Institut National de la Recherche Agronomique, Centre de Tours-Nouzilly, 37380 Nouzilly, France

Abstract

ABSTRACT Abortion, placental and fetal colonization, and levels of gamma interferon were analyzed for four Chlamydophila abortus strains presenting antigenic variations in a mouse model. Expression of virulence of these strains varied and indicated that abortion was not directly related to the number of bacteria in the placenta, and thus, other factors may have an important role in activating the abortion process.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference37 articles.

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3. Brown, A. S., M. L. Ammos, M. F. Lavin, A. A. Girjes, P. Timms, and J. B. Woolcock. 1988. Isolation and typing of a strain of Chlamydia psittaci from Angora goats. Aust. Vet. J.65:288-289.

4. Kinetics of Infection and Effects on Placental Cell Populations in a Murine Model of Chlamydia psittaci -Induced Abortion

5. Buendia, A. J., J. Sanchez, L. Del Rio, B. Garces, M. C. Gallego, M. R. Caro, A. Bernabe, and J. Salinas. 1999. Differences in the immune response against ruminant chlamydial strains in a murine model. Vet. Res.30:495-507.

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