Cometabolism of m -Chlorobenzoate by an Arthrobacter

Author:

Horvath R. S.1,Alexander M.1

Affiliation:

1. Laboratory of Soil Microbiology, Department of Agronomy, Cornell University, Ithaca, New York 14850

Abstract

Twenty isolates representing nine bacterial genera were obtained from enrichment cultures and were shown to cometabolize one or more of 22 substituted benzoates. One of the isolates, an Arthrobacter sp., cometabolized m -chlorobenzoate to a product identified as 4-chlorocatechol by thin-layer chromatography and ultraviolet and infrared spectroscopy. The data indicate that cometabolism by the arthrobacter results from the formation of products by its benzoate-oxiding enzyme system that are not acted upon by the catechol-metabolizing enzymes of the bacterium.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference19 articles.

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2. Effect of chemical structure on microbial degradation of substituted benzenes;Alexander M.;J. Agr. Food Chem.,1966

3. Colorimetric determination of the components of 3,4-dihydroxyphenylalanine-tyrosine mixtures;Arnow L. E.;J. Biol. Chem.,1937

4. Oxidation of alkylsubstituted cyclic hydrocarbons by a Nocardia during growth on n-alkanes;Davis J. B.;Appl. Microbiol.,1961

5. Foster J. W. 1962. Bacterial oxidation of hydrocarbons p. 241-271. In 0. Hayaishi (ed.) The oxygenases. Academic Press Inc. New York.

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