Identifying Mixed Mycobacterium tuberculosis Infection and Laboratory Cross-Contamination during Mycobacterial Sequencing Programs-Reference-Cited by-同舟云学术

Identifying Mixed Mycobacterium tuberculosis Infection and Laboratory Cross-Contamination during Mycobacterial Sequencing Programs

Published:2018-11 Issue:11 Volume:56 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Wyllie David H.¹²³^ORCID,Robinson Esther⁴,Peto Tim¹³,Crook Derrick W.¹³,Ajileye Adebisi⁴,Rathod Priti⁴,Allen Rosemarie⁴,Jarrett Lisa⁴,Smith E. Grace⁴,Walker A. Sarah¹³

Affiliation:

1. Nuffield Department of Medicine, John Radcliffe Hospital, Oxford, United Kingdom

2. Public Health England Academic Collaborating Centre, John Radcliffe Hospital, Oxford, United Kingdom

3. The National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Healthcare Associated Infections and Antimicrobial Resistance at University of Oxford, Oxford, United Kingdom

4. Public Health England National Mycobacteriology Laboratory North and Central, Heartlands Hospital, Birmingham, United Kingdom

Abstract

The detection of laboratory cross-contamination and mixed tuberculosis infections is an important goal of clinical mycobacteriology laboratories. The objective of this study was to develop a method to detect mixtures of different Mycobacterium tuberculosis lineages in laboratories performing mycobacterial next-generation sequencing (NGS).

Funder

Wellcome Trust

Department of Health

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00923-18

Reference24 articles.

1. Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans

2. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains