Viral DNA-synthesizing intermediate complex isolated during assembly of bacteriophage phi X174-Reference-Cited by-同舟云学术

Viral DNA-synthesizing intermediate complex isolated during assembly of bacteriophage phi X174

Published:1976-08 Issue:2 Volume:19 Page:409-415
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Fujisawa H,Hayashi M

Abstract

A DNA protein complex that is a precursor of mature phi X174 phage was isolated. The complex sedimented with an S value of 50 in a sucrose gradient and contained phage DNA consisting of a replicative form molecule with an extended tail of single-stranded viral DNA. The viral-strand DNA ranged from one to two genomes in length. Proteins coded on the phi X174 genome as well as the host genome were associated with the viral DNA in the 50S precursor complex. Our results indicated that both viral DNA synthesis and cleavage of the growing viral-strand DNA occurred in the 50S complex.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.19.2.409-415.1976

Reference34 articles.

1. A nuclease specific for heat-denatured DNA isolated from a product of aspergillus oryzae;Ando T.;Biochim. Biophys. Acta,1966

2. The abortive replication of OX-174 DNA in recombination-deficient mutant of Escherichia coli;Denhardt D. T.;Proc. Natl. Acad. Sci. U.S.A.,1967

3. The mechanism of replication of SX-174 single-stranded DNA. VI. Requirement for ribonucleoside triphosphates and DNA polymerase III;Denhardt D. T.;Can. J. Biochem.,1973

4. The process of infection with bacteriophage OX-174. IV. Replication of the viral DNA in a synchronized infection;Denhardt D. T.;J. Mol. Biol.,1965

5. On the mechanisms of OX single-stranded DNA synthesis;Dressler D. H.;Nature (London),1968

Cited by 45 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. An Infectious Virus‐like Particle Built on a Programmable Icosahedral DNA Framework**;Angewandte Chemie;2022-12-07

2. An Infectious Virus‐like Particle Built on a Programmable Icosahedral DNA Framework**;Angewandte Chemie International Edition;2022-12-07

3. Low-Temperature Adaptation Targets Genome Packing Reactions in an Icosahedral Single-Stranded DNA Virus;Journal of Virology;2022-04-13

4. Asymmetry in icosahedral viruses;Current Opinion in Virology;2019-06

5. Coat Protein Mutations That Alter the Flux of Morphogenetic Intermediates through the ϕX174 Early Assembly Pathway;Journal of Virology;2017-12-15