Bacteriophages as Adjuvant to Antibiotics for the Treatment of Periprosthetic Joint Infection Caused by Multidrug-Resistant Pseudomonas aeruginosa-Reference-Cited by-同舟云学术

Bacteriophages as Adjuvant to Antibiotics for the Treatment of Periprosthetic Joint Infection Caused by Multidrug-Resistant Pseudomonas aeruginosa

Published:2019-12-20 Issue:1 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Tkhilaishvili Tamta¹²,Winkler Tobias¹²,Müller Michael¹²,Perka Carsten¹²,Trampuz Andrej¹²

Affiliation:

1. Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Center for Musculoskeletal Surgery, Berlin, Germany

2. Berlin-Brandenburg Center for Regenerative Therapies, Charité—Universitätsmedizin Berlin, Berlin, Germany

Abstract

We documented the adjunctive bacteriophage therapy to treat a chronic relapsing periprosthetic joint infection of the knee and chronic osteomyelitis of the femur caused by multidrug-resistant Pseudomonas aeruginosa . The combined antibiotic-phage treatment eradicated the infection, and no side effects to phages were observed.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00924-19

Reference23 articles.

1. Prosthetic-Joint Infections

2. Osteoarticular infection caused by MDRPseudomonas aeruginosa: the benefits of combination therapy with colistin plus β-lactams

3. Current review-The rise of bacteriophage as a unique therapeutic platform in treating peri-prosthetic joint infections

4. Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria

5. Use of bacteriophages in the treatment of colistin-only-sensitive Pseudomonas aeruginosa septicaemia in a patient with acute kidney injury—a case report

Cited by 107 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Phage therapy for bone and joint infections: A comprehensive exploration of challenges, dynamics, and therapeutic prospects;Journal of Global Antimicrobial Resistance;2024-12

2. Pharmacokinetics and pharmacodynamics of bacteriophage therapy: a review with a focus on multidrug-resistant Gram-negative bacterial infections;Clinical Microbiology Reviews;2024-09-12

3. Bacteriophage therapy as an innovative strategy for the treatment of Periprosthetic Joint Infection: a systematic review;International Orthopaedics;2024-09-10

4. Isolation and Biological Characteristics of a Novel Phage and Its Application to Control Vibrio Parahaemolyticus in Shellfish Meat;Foodborne Pathogens and Disease;2024-08-01

5. Characterization of the novel broad-spectrum lytic phage Phage_Pae01 and its antibiofilm efficacy against Pseudomonas aeruginosa;Frontiers in Microbiology;2024-07-17