Emergence of fluconazole-resistant strains of Blastoschizomyces capitatus causing nosocomial infections in cancer patients

Author:

D'Antonio D1,Mazzoni A1,Iacone A1,Violante B1,Capuani M A1,Schioppa F1,Romano F1

Affiliation:

1. Servizio di Microbiologia Clinica del Dipartimento di Ematologia e della Trasfusione, Ospedale Santo Spirito, Pescara, Italy.

Abstract

Blastoschizomyces capitatus strains resistant to fluconazole were isolated in three cancer patients. All of the strains had identical genomic DNA restriction profiles. Our findings give evidence for the emergence of fluconazole-resistant B. capitatus and suggest a nosocomial acquisition emanating from a common source within the hospital environment.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference17 articles.

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2. Trichosporon capitatum septicemia in immunocompromised patients;Herbrecht R.;Pathol. Biol.,1990

3. Johnson E. M. D. W. Warnock C. A. Hitchcock and P. F. Troke. 1991. Two cases of fluconazole resistance in Candida glabrata p. 139. In Program and Abstracts of the XI Congress of the International Society for Human and Animal Mycology Montreal Canada.

4. Risk factors for candidemia in cancer patients: a case-control study;Karabinis A.;J. Clin. Microbiol.,1988

5. Disseminated Trichosporon capitatum infection in a patient with acute leukemia undergoing bone marrow transplantation;Liu K. L.;Bone Marrow Transplant.,1990

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