Author:
Ibrahim A B,Vyas G N,Perkins H A
Abstract
A total of 69 persons were investigated for assessment of cell-mediated and humoral immunity to hepatitis B surface antigen (HBsAg). Three groups, each consisting of 20 normal persons, 20HBsAg carriers, and 20 convalescent hepatitis B patients, were studied for HBsAg, anti-HBs, and leukocyte migration inhibition with purified HBsAg. Sequential sampling if an additional group of nine acute hepatitis B patients defined the cellular and humoral immune response to HBsAg. The antigen was eliminated rapidly by mounting of cell-mediated immune response detectable for a limited period, followed by antibody response in relatively few patients moore than 3 months after clearance of circulating HBsAg.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference25 articles.
1. A "new;Blumberg B. S.;J. Amer. Med. Ass.,1965
2. Center for Disease Control. 1974. Nomenclature of antigens associated with viral hepatitis type B. p. 29. Morbidity and Mortality Weekly Report. vol. 23: Center for Disease Control Atlanta Georgia.
3. The emerging epidemiology of hepatitis B antigen;Cherubin C. E.;Ann. Intern. Med.,1973
4. Inhibitory effect of Australia positive sera on in vitro-stimulated T Iymphocytes;Clot J.;Lancet,1973
5. Epidemiology of serum hepatitis;Cossart Y. E.;Brit. Med. Bull.,1972
Cited by
39 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献