Use of a novel air separation system in a fed-batch fermentative culture of Escherichia coli-Reference-Cited by-同舟云学术

Use of a novel air separation system in a fed-batch fermentative culture of Escherichia coli

Published:1989-05 Issue:5 Volume:55 Page:1305-1307
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Fass R¹,Clem T R¹,Shiloach J¹

Affiliation:

1. Biotechnology Unit, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892.

Abstract

A novel air separation system based on permeable membrane gas separation technology was used to cultivate Escherichia coli. The system fulfilled the dissolved oxygen requirements of a culture of E. coli grown on a glucose synthetic medium at a high and constant growth rate of 0.55 h-1. A biomass yield of 45 g (dry weight) per liter was achieved, and no by-product inhibition by acetate or CO2 was observed.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.55.5.1305-1307.1989

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